DESCRIPTION
Sorry, this bug happened because of the DLSS/FSR plugin... I'll try to fix the issue in the future; however, here's a temp fix for that.
Please delete the file under:newGiantess/Saved/newGiantess_PCD3D_SM6.upipelinecache
Also, if you're using the AMD driver and cannot run the game, try this:
Sorry for the inconvenience... I hope the new upgrade (switching DLSS/FSR version) may help with solving this issue.